Pharmacology

  • In the current era of innovation in Lifesciences, be it drug discovery, biotechnology, medical devices or natural products, a key factor in translating an exciting idea to reality or evaluation of a newly designed molecule or product is to obtain robust and quality data from optimally designed experiments.
  • We at TheraIndx endeavor to meet these criteria. TheraIndx offers wide range of Animal disease models covering a variety of therapeutic areas such as infection, Oncology, Metabolic Disease, Wound healing, Inflammation, CNS etc.

     "We establish and validate disease models based on research needs."

Infection Models-Mouse:

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  • Thigh Infection - neutropenic [Gram positive and Gram negative pathogens]
  • Septicaemia - neutropenic [Gram positive and Gram negative pathogens]
  • Lung Infection - neutropenic [Gram positive and Gram negative pathogens]
  • Infection models to Identify PK/PD parameters for Efficacy
  • Ascending Urinary Tract Infection
  • Excision & Incision wound Infection
  • Foreign Body Infection
  • Diabetes Wound Infection
  • Burn wound Infection
  • Skin Infection (Candida albicans)
  • Skin Infection (S. aureus)
  • Dermatophytosis
  • Mouse Ear Infection
  • Complicated-UTI (c-UTI)
  • Intra-abdominal infection
  • Septicaemia model (CLP)
  • Dengue
  • Malaria
  • African Trypanosoma
  • Leishmania
  • Nasal decolonization

Infection Models-Rat:

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  • Thigh Infection - neutropenic [Gram positive and Gram Negative pathogens]
  • Septicaemia -neutropenic [Gram positive and Gram Negative pathogens]
  • Lung Infection (with ELF-PK)- neutropenic [Gram positive and Gram Negative pathogens]
  • Infection models to Identify PK/PD parameters for Efficacy
  • Ascending Urinary Tract Infection
  • Osteomyelitis (with Bone PK)
  • Foreign Body infection
  • Excision & Incision wound Infection
  • Burn wound Infection
  • Skin infection (Candida albicans)
  • Dermatophytosis
  • Heat Killed P. acnes Induced Paw Edema
  • Endocarditis
  • P. Carinii
  • Nasal decolonization

 

Oncology Models:

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  • Xenograft
  • Orthotopic
  • Syngeneic
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Wound Healing Models:

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  • Excision & Incision wound
  • Diabetes wound
  • Burn wound
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Metabolic Disease Models:

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  • Chronic Kidney Disorder Model
  • Acute Kidney Injury Model
  • Alopecia Models [Testosterone, DHT]
  • Kidney fibrosis
  • Liver fibrosis
  • NAFLD/NASH
  • Obesity
  • Liver injury/Hepatoprotection
  • Dyslipidaemia
  • Diabetes (type 1)
  • Diabetes (type 2)
  • Diabetes induced Nephropathy
  • Diabetes induced Atherosclerosis

 

Inflammation Models

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  • Arthritis & RA (CIA, RIA, Antibody Induced)
  • Paw Edema (Carrageenan)
  • Chronic Inflammation models
  • Collagen Induced RA
  • DSS/TNBS induced Colitis
  • Chronic Inflammatory Pain model
  • Osteoporosis in Rats

Neurology Models:

  • LPS induced Neuro inflammation model

CNS Models

  • Alzheimer’s disease
  • Parkinson’s disease
  • Antiepileptic Activity

Accreditations

theme-img"Where science and responsible animal care connect."